MAGNOLOL ENHANCES THE THERAPEUTIC EFFECTS OF TRAIL THROUGH DR5 UPREGULATION AND DOWNREGULATION OF C-FLIP AND MCL-1 PROTEINS IN CANCER CELLS

Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells

Magnolol is a biologically active compound, isolated from the Chinese herb Magnolia, that regulates antiproliferative, anticancer, antiangiogenic and antimetastatic activities.We found that magnolol sensitizes TRAIL-induced apoptotic Heel Sleeve cell death via upregulation of DR5 and downregulation of cellular FLICE-inhibitory protein (c-FLIP) and

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THE GENDER REVEAL PARTY

This article explores the popularization of gender reveal parties and considers what they can tell us about current societal expectations around gender, parenthood, and consumption.Gender reveal parties are events in which expectant parents reveal, or even learn, the sex of the child-to-be through a surprise display of something pink or blue, typic

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Avian Reproduction in a Warming World

Weather influences both the distribution and life-history strategies of birds.Temperature ranks amongst the more important weather OPTICS parameters in this regard since warming springs in temperate and high latitudes and more frequent heat-waves globally have caused major changes in breeding phenology and negatively affected adult and juvenile sur

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Recycled polymer: Green roads for polyester plastics

Plastics are integral to numerous significant social advancements.Nonetheless, their contribution to environmental pollution and climate crises cannot be disregarded, as their negative impact on the environment increases with incremental production capacity and demand.Concerted global action is urgently required to promote the green recycle of plas

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